The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism
- Stephanos Pavlides
- Aristotelis Tsirigos
- et al.
- 2014
- Cell Cycle
Paper
Publications
11 results for Ubaldo E. Martinez-Outschoorn
Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism
- Gloria Bonuccelli
- Aristotelis Tsirigos
- et al.
- 2014
- Cell Cycle
PaperKetones and lactate increase cancer cell "stemness", driving recurrence, metastasis and poor clinical outcome in breast cancer: Achieving personalized medicine via metabolo-genomics
- Ubaldo E. Martinez-Outschoorn
- Marco Prisco
- et al.
- 2014
- Cell Cycle
PaperMitochondria "fuel" breast cancer metabolism: Fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells
- Federica Sotgia
- Diana Whitaker-Menezes
- et al.
- 2014
- Cell Cycle
PaperLoss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": A transcriptional informatics analysis with validation
- Stephanos Pavlides
- Aristotelis Tsirigos
- et al.
- 2014
- Cell Cycle
PaperGlycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: Evidence for stromal-epithelial metabolic coupling
- Gemma Migneco
- Diana Whitaker-Menezes
- et al.
- 2014
- Cell Cycle
PaperIs cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism
- Adam Ertel
- Aristotelis Tsirigos
- et al.
- 2014
- Cell Cycle
ReviewUnderstanding the "lethal" drivers of tumor-stroma co-evolution: Emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment
- Michael P. Lisanti
- Ubaldo E. Martinez-Outschoorn
- et al.
- 2014
- Cancer Biology and Therapy
ReviewThe autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox
- Ubaldo E. Martinez-Outschoorn
- Diana Whitaker-Menezes
- et al.
- 2014
- Cell Cycle
ReviewJNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: Connecting fibrosis, inflammation, and stemness for cancer prevention
- Michael P. Lisanti
- Aristotelis Tsirigos
- et al.
- 2013
- Cell Cycle
Paper